Gene Panel Testing For Hereditary Breast Cancer

Genetic testing does not detect breast cancer itself it identifies people who are at higher than average risk and helps us to determine the best ways to screen them hilliard said.

Gene panel testing for hereditary breast cancer.

This single reliable test provides more information for women suspected to have hereditary cancer predisposition particularly for breast and ovarian cancers. At this time the association of these genes with breast cancer remains uncertain. This test includes both well established breast cancer susceptibility genes as well as candidate genes with limited evidence of an association with breast cancer. However some clinicians may wish to include genes that may prove to be clinically significant in the future.

Studies have shown that testing with myriad myrisk increases mutation detection between 40 and 50 percent. The breast cancer comprehensive panel examines 20 genes associated with an increased risk for hereditary breast cancer. In addition to the primary panel clinicians can also choose to include 14 genes that have preliminary evidence of an association with breast cancer. Is ideal for patients with a clinical suspicion of hereditary breast or ovarian cancer who only wish assessment of genes with established management guidelines.

Your doctor might suggest testing using a multigene panel which looks for mutations in several genes at the same time including brca1 and brca2. These genes can be added at no additional charge. Gene panel testing for hereditary breast cancer inherited predisposition to breast cancer is explained only in part by mutations in the brca1 and brca2 genes. Genetic testing for hereditary breast and ovarian cancer looks for mutations in the brca1 and brca2 genes.

The myriad myrisk hereditary cancer test is a 35 gene panel that identifies an elevated risk for eight hereditary cancers. Genetic testing of these. Myriad myrisk captures more mutation carriers than bracanalysis and colaris combined.